Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus.

Cell - 15 Jan 1993

Liao X, Butow R A

Abstract excerpt

The expression of some nuclear genes is sensitive to the functional state of mitochondria, a process we term retrograde regulation. Here we show that retrograde regulation of the yeast CIT2 gene encoding peroxisomal citrate synthase depends on a new class of upstream activation site element (UASr) and two previously unidentified genes, RTG1 and RTG2. RTG1 encodes a protein of 177 amino acids with similarity to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Fungal Proteins

Share to Genes, Fungal

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 8422683
DOI: 10.1016/0092-8674(93)90050-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus.PMID 8422683Read ↗

RTG genes in yeast that function in communication between mitochondria and the nucleus are also required for expression of genes encoding peroxisomal proteins.Semantic proximity Read ↗

A transcriptional switch in the expression of yeast tricarboxylic acid cycle genes in response to a reduction or loss of respiratory function.Semantic proximity Read ↗

Transactivation by Rtg1p, a basic helix-loop-helix protein that functions in communication between mitochondria and the nucleus in yeast.Semantic proximity Read ↗

Interorganellar communication. Altered nuclear gene expression profiles in a yeast mitochondrial dna mutant.Semantic proximity Read ↗

The retrograde response links metabolism with stress responses, chromatin-dependent gene activation, and genome stability in yeast aging.Semantic proximity Read ↗

The Saccharomyces cerevisiae RTG2 gene is a regulator of aconitase expression under catabolite repression conditions.Semantic proximity Read ↗

Retrograde response to mitochondrial dysfunction is separable from TOR1/2 regulation of retrograde gene expression.Semantic proximity Read ↗

Functional and Regulatory Profiling of Energy Metabolism in Fission YeastSemantic proximity Read ↗

Functional analysis of the Saccharomyces cerevisiae YFR021w/YGR223c/YPL100w ORF family suggests relations to mitochondrial/peroxisomal functions and amino acid signalling pathways.Semantic proximity Read ↗

Metabolic and developmental effects resulting from deletion of the citA gene encoding citrate synthase in Aspergillus nidulans.Semantic proximity Read ↗

Regulation of respiratory growth by Ras: the glyoxylate cycle mutant, cit2Delta, is suppressed by RAS2.Semantic proximity Read ↗

Functional and regulatory profiling of energy metabolism in fission yeast.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.