Viral Internal Ribosome Entry Site Elements: Novel Ribosome-RNA Complexes and Roles in Viral Pathogenesis

Abstract excerpt

Viruses have multifaceted approaches to ensure that viral genome amplification can be achieved in an efficient and, in some instances, a cell-type-specific manner. To accomplish this task, some viruses encode their own polymerases which selectively amplify the viral genomes; other viruses have evolved a variety of ways to compete directly with the host cell for factors that are needed for viral gene replication...

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