Biochemical comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins. Delineation of a limit Cdc42 GTPase-activating protein domain.

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Article

Biochemical comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins. Delineation of a limit Cdc42 GTPase-activating protein domain.

The Journal of biological chemistry - 25 Nov 1993

Zheng Y, Hart M J, Shinjo K, Evans T, Bender A, Cerione R A

Abstract excerpt

The Bem2 and Bem3 proteins, which appear to play roles in the regulation of bud site formation in Saccharomyces cerevisiae, show striking homology to a number of proteins that compose a family of GTPase-activating proteins (GAPs) for the rho-subgroup of ras-related GTP-binding proteins. These members include human platelet GAP for Cdc42Hs (the human homolog of a S. cerevisiae GTP-binding protein that regulates...

Topics

Amino Acid Sequence
Enzyme Activation
Fungal Proteins
GTP Phosphohydrolases
GTP-Binding Proteins
GTPase-Activating Proteins
Glutathione Transferase
Humans
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proteins

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Sequence Deletion

Sequence Homology, Amino Acid

cdc42 GTP-Binding Protein

ras GTPase-Activating Proteins

Source

Open in PubMed

Identifiers

PMID: 8227021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8227021-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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