Article
Mutation-deletion analysis of a Ca(2+)-dependent phospholipid binding (CaLB) domain within p120 GAP, a GTPase-activating protein for p21 ras.
The Biochemical journal - 15 Apr 1995
Gawler D J, Zhang L J, Moran M F
Abstract excerpt
p120 GAP is a GTPase activating protein for p21 ras. It is a multidomain protein which exhibits sequence similarity with other GTPase-activating proteins, src, pleckstrin and a central portion of the protein kinase C conserved region 2 domain known as CaLB (Ca(2+)-dependent phospholipid-binding)....
Topics
- Amino Acid Sequence
- Binding Sites
- Calcium
- DNA Mutational Analysis
- GTPase-Activating Proteins
- Humans
- Molecular Sequence Data
- Mutation
- Oncogene Protein p21(ras)
- Phospholipids
- Proteins
- Recombinant Fusion Proteins
- Sequence Deletion
- ras GTPase-Activating Proteins