Article
The role of cell adhesion molecule in cancer progression and its application in cancer therapy.
Acta biochimica Polonica - 1 Jan 2004
Okegawa Takatsugu, Pong Rey-Chen, Li Yingming, Hsieh Jer-Tsong
Abstract excerpt
Multiple and diverse cell adhesion molecules take part in intercellular and cell-extracellular matrix interactions of cancer. Cancer progression is a multi-step process in which some adhesion molecules play a pivotal role in the development of recurrent, invasive, and distant metastasis. A growing body of evidence indicates that alterations in the adhesion properties of neoplastic cells play a pivotal role in the...
Topics
- Animals
- Antigens, CD
- Antigens, Differentiation
- Cadherins
- Cell Adhesion
- Cell Adhesion Molecules
- Coxsackie and Adenovirus Receptor-Like Membrane Protein
- DCC Receptor
- Disease Progression
- Extracellular Matrix
- Glycoproteins
- Humans
- Neoplasm Metastasis
- Neoplasms
- Phenotype
- Receptors, Cell Surface
- Receptors, Virus
- Tumor Suppressor Proteins