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Article

Expression and function of calcium binding domain chimeras of the integrins alpha(IIb) and alpha(5).

The Journal of biological chemistry - 3 Mar 2000

Gidwitz S, Lyman S, White G C

Abstract excerpt

To further identify amino acid domains involved in the ligand binding specificity of alpha(IIb)beta(3), chimeras of the conserved calcium binding domains of alpha(IIb) and the alpha subunit of the fibronectin receptor alpha(5)beta(1) were constructed. Chimeras that replaced all four calcium binding domains, replaced all but the second calcium binding domain of alpha(IIb) with those of alpha(5), or deleted all...

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Identifiers

PMID: 10692478
DOI: 10.1074/jbc.275.9.6680

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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