Article
Homophilic intercellular adhesion mediated by C-CAM is due to a domain 1-domain 1 reciprocal binding.
Experimental cell research - 15 Sept 1996
Wikström K, Kjellström G, Obrink B
Abstract excerpt
The cell adhesion molecule C-CAM belongs to the immunoglobulin superfamily and is expressed in epithelia, vessel endothelia, and hematopoietic cells. Differential splicing gives rise to different isoforms, of which the major two are C-CAM1 and C-CAM2, which both have four Ig-like domains in their extracellular portions, but differ in their cytoplasmic domains. Two different allelic variants of C-CAM, named a and...
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