Shared operator recognition specificity between Trp repressor and the repressors of bacteriophage 434.

doi:10.1016/0022-2836(91)90516-9

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Article

Shared operator recognition specificity between Trp repressor and the repressors of bacteriophage 434.

Journal of molecular biology - 20 Feb 1991

Somerville R L, Bogosian G, Zeilstra-Ryalls J H

Abstract excerpt

Trp repressor is the only DNA-binding regulatory protein having a helix-turn-helix motif that has been reported to engage its operator target by a mechanism termed indirect readout: the Trp repressor-DNA interface is replete with hydrogen bonds between amino acid residues and non-esterified oxyge...

Topics

Amino Acid Sequence
Bacterial Proteins
Base Sequence
Coliphages
Escherichia coli
Hydrogen Bonding
Molecular Sequence Data
Mutation
Operator Regions, Genetic
Promoter Regions, Genetic
Repressor Proteins
Tryptophan
Viral Proteins

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