chpA and chpB, Escherichia coli chromosomal homologs of the pem locus responsible for stable maintenance of plasmid R100.

doi:10.1128/jb.175.21.6850-6856.1993

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Article

chpA and chpB, Escherichia coli chromosomal homologs of the pem locus responsible for stable maintenance of plasmid R100.

Journal of bacteriology - 1 Nov 1993

Masuda Y, Miyakawa K, Nishimura Y, Ohtsubo E

Abstract excerpt

The pem locus is responsible for stable maintenance of plasmid R100 and consists of two genes, pemI and pemK. The pemK gene product is a growth inhibitor, while the pemI gene product is a suppressor of this inhibitory function. We found that the PemI amino acid sequence is homologous to two open reading frames from Escherichia coli called mazE and orf-83, which are located at 60 and 100 min on the chromosome,...

Topics

Amino Acid Sequence
Bacterial Proteins
Base Sequence
Chromosomes, Bacterial
Cloning, Molecular
Consensus Sequence
DNA Primers
DNA-Binding Proteins
Escherichia coli
Escherichia coli Proteins
Genes, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Kinetics

Molecular Sequence Data

Mutagenesis, Insertional

Open Reading Frames

Plasmids

Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 8226627
DOI: 10.1128/jb.175.21.6850-6856.1993
PMCID: PMC206809

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8226627-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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