Article
The partitioning activity of the RK2 central control region requires only incC, korB and KorB-binding site O(B)3 but other KorB-binding sites form destabilizing complexes in the absence of O(B)3.
Microbiology (Reading, England) - 1 Dec 1998
Williams D Ross, Macartney Donia P, Thomas Christopher M
Abstract excerpt
The sector of the genome of broad-host-range IncP plasmid RK2 from kb coordinate 54.0 to 60.0 confers an active partitioning phenotype, increasing the segregational stability of low-copy-number unstable plasmids. This Par region encodes the central control operon (korA, incC, korB, korF and korG)...
Topics
- Bacterial Proteins
- Binding Sites
- Escherichia coli
- Gene Dosage
- Gene Expression Regulation, Bacterial
- Mutagenesis
- Mutation
- Operon
- Phenotype
- R Factors
- Replicon
- Repressor Proteins