Article
Identification of an uncommon haptoglobin type using DNA and protein analysis.
Human genetics - 1 Oct 1993
Marles S L, McAlpine P J, Zelinski T, Phillips S, Maeda N, Greenberg C R
Abstract excerpt
The inherited variations in haptoglobin phenotypes are attributed to the homozygous and heterozygous combinations of three common autosomal alleles: HP*1F, HP*1S and HP*2. HP*1F and HP*1S encode polypeptides that differ by two amino acids at positions 51 and 53. The formation of HP*2 is postulated to have resulted from a breakage and subsequent reunion event at non-homologous positions of two HP*1 alleles. The...
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