Identification of an uncommon haptoglobin type using DNA and protein analysis.

doi:10.1007/BF01247336

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Article

Identification of an uncommon haptoglobin type using DNA and protein analysis.

Human genetics - 1 Oct 1993

Marles S L, McAlpine P J, Zelinski T, Phillips S, Maeda N, Greenberg C R

Abstract excerpt

The inherited variations in haptoglobin phenotypes are attributed to the homozygous and heterozygous combinations of three common autosomal alleles: HP*1F, HP*1S and HP*2. HP*1F and HP*1S encode polypeptides that differ by two amino acids at positions 51 and 53. The formation of HP*2 is postulate...

Topics

Alleles
Blood Proteins
Blotting, Southern
Corneal Dystrophies, Hereditary
DNA
Electrophoresis, Starch Gel
Female
Genotype
Haptoglobins
Humans
Male
Nucleic Acid Hybridization
Phenotype

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