Article
Duplication within the haptoglobin Hp2 gene.
Nature - 1 Jan 2000
Maeda N, Yang F, Barnett D R, Bowman B H, Smithies O
Abstract excerpt
DNA sequencing shows that the intragenic duplication within the human haptoglobin Hp2 allele was formed by a non-homologous, probably random, crossing-over within different introns of two Hp1 genes, probably in an Hp1F / Hp1S heterozygote.
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Crossing Over, Genetic
- DNA Restriction Enzymes
- Genes
- Genotype
- Haptoglobins
- Heterozygote
- Humans