Chromosome-based method for rapid computer simulation in human genetic linkage analysis.

doi:10.1002/gepi.1370100402

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Article

Chromosome-based method for rapid computer simulation in human genetic linkage analysis.

Genetic epidemiology - 1 Jan 1993

Terwilliger J D, Speer M, Ott J

Abstract excerpt

Computer-based simulation has been an important method in human linkage analysis for a long time. Typically, such analyses have been performed by simulating a set of linked markers according to the intermarker recombination fractions, under the assumption of no genetic interference. A novel appro...

Topics

Chromosome Mapping
Chromosomes, Human
Computer Simulation
Female
Genetic Linkage
Genetic Markers
Humans
Male
Pedigree
Phenotype

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