Article
Chromosome-based method for rapid computer simulation in human genetic linkage analysis.
Genetic epidemiology - 1 Jan 1993
Terwilliger J D, Speer M, Ott J
Abstract excerpt
Computer-based simulation has been an important method in human linkage analysis for a long time. Typically, such analyses have been performed by simulating a set of linked markers according to the intermarker recombination fractions, under the assumption of no genetic interference. A novel approach is proposed in which such simulations can be performed using chromosome-based methods, rather than traditional...
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