Article
A haplotype-linkage analysis method for estimating recombination rates using dense SNP trio data.
Genetic epidemiology - 1 Feb 2007
Zhao Lue Ping, Li Shuying Sue, Shen Fumin
Abstract excerpt
Meiotic recombination is an important evolution force in shaping human genomes and creating human diversity. Recent explorations suggest that meiotic recombination events tend to happen in certain regions of the genome, leading to the hypothesis of recombination hot spots. To identify such hot spots, we describe an empirical method for estimating the recombination rate, which reflects both historical and current...
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