Article
Analysis of human meiotic recombination events with a parent-sibling tracing approach.
BMC genomics - 26 Aug 2011
Lee Yun-Shien, Chao Angel, Chen Chun-Houh, Chou Tina, Wang Shih-Yee Mimi, Wang Tzu-Hao
Abstract excerpt
BACKGROUND: Meiotic recombination ensures that each child inherits distinct genetic materials from each parent, but the distribution of crossovers along meiotic chromosomes remains difficult to identify. In this study, we developed a parent-sibling tracing (PST) approach from previously reported methods to identify meiotic crossover sites of GEO GSE6754 data set. This approach requires only the single nucleotide...
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