Article
Targeting of pro-opiomelanocortin to the regulated secretory pathway may involve cooperation between different protein domains.
Molecular and cellular endocrinology - 1 Aug 1993
Chevrier D, Fournier H, Nault C, Zollinger M, Crine P, Boileau G
Abstract excerpt
The structure of pro-opiomelanocortin (POMC) can be divided into three main domains: an NH2-terminal domain formed by the NH2-terminal glycopeptide and the joining peptide, a central domain corresponding to the adrenocorticotropin sequences and a COOH-terminal domain containing the beta-lipotropi...
Topics
- Adrenocorticotropic Hormone
- Amino Acid Sequence
- Amino Acids
- Animals
- Cell Line, Transformed
- DNA
- Fluorescent Antibody Technique
- Gene Deletion
- Immunoblotting
- Mice
- Microscopy, Immunoelectron
- Molecular Sequence Data
- Mutation
- Neuroblastoma
- Pro-Opiomelanocortin
- Radioimmunoassay
- Tumor Cells, Cultured