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Article

Targeting of pro-opiomelanocortin to the regulated secretory pathway may involve cooperation between different protein domains.

Molecular and cellular endocrinology - 1 Aug 1993

Chevrier D, Fournier H, Nault C, Zollinger M, Crine P, Boileau G

Abstract excerpt

The structure of pro-opiomelanocortin (POMC) can be divided into three main domains: an NH2-terminal domain formed by the NH2-terminal glycopeptide and the joining peptide, a central domain corresponding to the adrenocorticotropin sequences and a COOH-terminal domain containing the beta-lipotropin sequences. Expression of POMC in neuroendocrine cell lines such as the mouse neuroblastoma Neuro2A cells results in...

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Identifiers

PMID: 8224524
DOI: 10.1016/0303-7207(93)90170-o

Genes

POMC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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