Article
An atypical carcinoid tumor of the lung with mutations in the p53 gene and the retinoblastoma gene.
Chest - 1 Nov 1993
Hiyama K, Hasegawa K, Ishioka S, Takahashi N, Yamakido M
Abstract excerpt
Molecular analysis of a metastatic lesion of an atypical carcinoid tumor of the lung obtained from a 77-year-old man at autopsy revealed a point mutation in the p53 gene and a deletion in the retinoblastoma (Rb) mRNA. This case suggests that both these antioncogenes may be involved in the progression of atypical carcinoid tumor.
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