Article
Genetic alteration in carcinoid tumors of the lung.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia - 1 Jun 2003
Sugio Kenji, Osaki Toshihiro, Oyama Tsunehiro, Takenoyama Mitsuhiro, Hanagiri Takeshi, Morita Masaru, Yamazaki Koji, Nagashima Akira, Nakahashi Hisashi, Maehara Yoshihiko, Yasumoto Kosei
Abstract excerpt
Surgically resected specimens of 13 carcinoid tumors of the lung including nine typical carcinoids and four atypical carcinoids, and eight salivary gland type carcinomas (six mucoepidermoid carcinomas and two adenoid cystic carcinomas) were analyzed regarding p53 expression, loss of heterozygosity (LOH) in chromosome 3p, 9p, and K-ras mutation. The overexpression of p53 was identified in four atypical carcinoid...
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