Article
Autoimmune renal disease and tumour necrosis factor beta gene polymorphism.
Clinical nephrology - 1 Aug 1993
Medcraft J, Hitman G A, Sachs J A, Whichelow C E, Raafat I, Moore R H
Abstract excerpt
The genes encoding tumour necrosis factors (TNF) are located within the major histocompatibility complex. Since TNF may be involved in the pathogenesis of autoimmune disease the purpose of the present study was to investigate TNF beta gene polymorphism in two types of immune complex mediated glom...
Topics
- Alleles
- Autoimmune Diseases
- DNA
- Diabetes Mellitus, Type 1
- Genotype
- Glomerulonephritis, IGA
- Glomerulonephritis, Membranous
- Haplotypes
- Humans
- Linkage Disequilibrium
- Lymphotoxin-alpha
- Major Histocompatibility Complex
- Polymorphism, Genetic
