Article
Polymorphism of the cytokine genes and IgA nephropathy.
Kidney international - 1 Mar 2002
Syrjänen Jaana, Hurme Mikko, Lehtimäki Terho, Mustonen Jukka, Pasternack Amos
Abstract excerpt
BACKGROUND: IgA nephropathy (IgAN) is a form of chronic glomerulonephritis of unknown etiology and pathogenesis. Cytokine gene polymorphisms regulate cytokine production and play a role in immune and inflammatory responses; these immunological responses thus are possibly involved in the etiology and pathogenesis of IgAN. METHODS: We studied by polymerase chain reaction (PCR) polymorphisms of important cytokine...
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