Increased levels of circulating (TNF-α) is associated with (-308G/A) promoter polymorphism of TNF-α gene in Diabetic Nephropathy.

doi:10.1016/j.ijbiomac.2017.10.078

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Increased levels of circulating (TNF-α) is associated with (-308G/A) promoter polymorphism of TNF-α gene in Diabetic Nephropathy.

International journal of biological macromolecules - 1 Feb 2018

Umapathy Dhamodharan, Krishnamoorthy Ezhilarasi, Mariappanadar Vairamani, Viswanathan Vijay, Ramkumar Kunka Mohanram

Abstract excerpt

The crucial role of Tumor Necrosis Factor-α (TNF-α) on renal function in patients with Diabetic Nephropathy (DN) has been well documented. The present study was designed to investigate the association of TNF-α [-308G/A, (rs1800629)] single nucleotide polymorphism (SNP) on the susceptibility to DN subjects and to correlate it with the plasma levels of TNF-α along with circulatory TNF-α receptor super family...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Albuminuria

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Anthropometry

Share to Diabetic Nephropathies

Share to Logistic Models

Share to Receptors, Tumor Necrosis Factor

Share to Solubility

Share to Statistics, Nonparametric

Share to Tumor Necrosis Factor-alpha

Source

Open in PubMed

Identifiers

PMID: 29042282
DOI: 10.1016/j.ijbiomac.2017.10.078

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased levels of circulating (TNF-α) is associated with (-308G/A) promoter polymorphism of TNF-α gene in Diabetic Nephropathy.PMID 29042282Read ↗

TNF-α-308G/A polymorphism associated with TNF-α protein expression in patients with diabetic nephropathy.Semantic proximity Read ↗

Association of tumor necrosis factor (TNF) promoter polymorphisms with plasma TNF-α levels and susceptibility to diabetic nephropathy in North Indian population.Semantic proximity Read ↗

Study the Association of Tumor Necrosis Factor Promoter Polymorphism with Type 2 Diabetic Nephropathy.Semantic proximity Read ↗

Effects of TNF-α-308G/A Polymorphism on the Risk of Diabetic Nephropathy and Diabetic Retinopathy: An Updated Meta-Analysis.Semantic proximity Read ↗

The role of the TNF-α gene -308 G/A polymorphism in the development of diabetic nephropathy: An updated meta-analysis.Semantic proximity Read ↗

Comparative analysis of TNF-α (-308) gene polymorphism in Turkish patients with type 2 diabetes developing nephropathy and/or neuropathy.Semantic proximity Read ↗

Genetic variations in key inflammatory cytokines exacerbates the risk of diabetic nephropathy by influencing the gene expression.Semantic proximity Read ↗

Association between polymorphisms of cytokine genes and diabetic nephropathy: A comprehensive systematic review and meta-analysis.Semantic proximity Read ↗

Investigations of associations between TNF-α promoter polymorphisms and genetic susceptibility to type 2 diabetes mellitus: A cross-sectional study in Chinese Han population.Semantic proximity Read ↗

Association of tumor necrosis factor alpha promoter polymorphism (TNF-α 238 G/A and TNF-α 308 G/A) with diabetic mellitus, diabetic retinopathy and diabetic nephropathy: a meta-analysis.Semantic proximity Read ↗

Association of IL-6, IL-10, and TNF-α gene polymorphism with malnutrition inflammation syndrome and survival among end stage renal disease patients.Semantic proximity Read ↗

Oxidative stress and its association with TNF-α-308 G/C and IL-1α-889 C/T gene polymorphisms in patients with diabetes and diabetic nephropathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.