Impact of pharmacogenetics on toxicological studies. Statistical implications.

Article

Impact of pharmacogenetics on toxicological studies. Statistical implications.

Journal of experimental animal science - 1 Sept 1993

Lovell D P

Abstract excerpt

Genetic differences in response to chemicals are probably ubiquitous. The implications of such genetic differences for the design of toxicological experiments is reviewed. The inclusion of genetic differences as factors in factorial experimental designs is illustrated by an experiment to investig...

Topics

Animals
Barbiturates
Drug-Related Side Effects and Adverse Reactions
Female
Genetic Variation
Humans
Male
Mice
Mice, Inbred Strains
Neoplasms
Pharmacogenetics
Rats
Toxicology

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