Toxicity testing and genetic quality control.

Article

Toxicity testing and genetic quality control.

Journal of experimental animal science - 1 Sept 1993

van Zutphen L F

Abstract excerpt

The genetic background of animals plays a major role in the outcome of toxicity tests. The use animals with a defined and standardized genetic variation as opposed to animals from an outbred strain may improve the quality of the tests and may reduce the numbers of animals to be used. In order to...

Topics

Animals
Animals, Laboratory
Drug-Related Side Effects and Adverse Reactions
Genetic Variation
Inbreeding
Mice
Mice, Inbred Strains
Quality Control
Rats
Rats, Inbred Strains
Toxicology

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