Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The roads from phenotypic variation to gene discovery: mutagenesis versus QTLs.

Nature genetics - 1 Aug 2000

Nadeau J H, Frankel W N

Abstract excerpt

In model organisms, chemical mutagenesis provides a powerful alternative to natural, polygenic variation (for example, quantitative trait loci (QTLs)) for identifying functional pathways and complex disease genes. Despite recent progress in QTLs, we expect that mutagenesis is will ultimately prov...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes
Share to Genetic Variation
Share to Linkage Disequilibrium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutagenesis

Share to Phenotype

Share to Quantitative Trait, Heritable

Source

Identifiers

PMID: 10932178
DOI: 10.1038/78051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10932178-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The roads from phenotypic variation to gene discovery: mutagenesis versus QTLs.PMID 10932178Read ↗

QTL analysis and genomewide mutagenesis in mice: complementary genetic approaches to the dissection of complex traits.Semantic proximity Read ↗

Frontiers in chemical genetics.Semantic proximity Read ↗

Mutagenomics: The Future of Genetic Screens.Semantic proximity Read ↗

Muta-genetics or muta-genomics: the feasibility of large-scale mutagenesis and phenotyping programs.Semantic proximity Read ↗

Chemical genetics: elucidating biological systems with small-molecule compounds.Semantic proximity Read ↗

Probabilistic analysis of recessive mutagenesis screen strategies.Semantic proximity Read ↗

Combining mutagenesis and genomics in the mouse--closing the phenotype gap.Semantic proximity Read ↗

Back to the Future: Mutant Hunts Are Still the Way To Go.Semantic proximity Read ↗

The utilization of quantitative trait loci in toxicogenetics.Semantic proximity Read ↗

Chemical genetics: where genetics and pharmacology meet.Semantic proximity Read ↗

[Advance in quantitative traits from phenotypic variation to gene discovery].Semantic proximity Read ↗

Genetic screens: A global map of genetic interactions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.