Article
The choice of animal model and reduction.
Alternatives to laboratory animals : ATLA - 1 Sept 2004
Festing Michael F W
Abstract excerpt
Careful choice of the animal model is essential, if research is to be conducted efficiently, by using the minimum number of animals in order to provide the maximum amount of information. Inbred strains of rodents provide an excellent way of controlling and investigating genetic variation in characters of interest and in response to experimental treatments. Outbred stocks, in which genetic and non-genetic factors...
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