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Article

Evidence should trump intuition by preferring inbred strains to outbred stocks in preclinical research.

ILAR journal - 1 Jan 2014

Festing Michael F W

Abstract excerpt

Inbred strains of mice such as C57BL and BALB/c are more widely used in published work than outbred stocks of mice such as ICR and CD-1. In contrast, outbred stocks of rats such as Wistar and Sprague-Dawley are more widely used than inbred strains such as F344 and LEW. The properties of inbred and outbred mice and rats are briefly reviewed, and it is concluded that, with some exceptions, there is a strong case...

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Identifiers

PMID: 25541542
DOI: 10.1093/ilar/ilu036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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