[Genetic predisposition and ovarian cancer].

Abstract excerpt

The genetic predisposition to epithelial ovarian cancer can be distinguished in two different forms: familial breast and/or ovarian cancer; familial colon, endometrium, ovarian cancer or HNPCC syndrome (hereditary non polyposis colorectal cancer). The BRCA1 and BRCA2 genes are involved in familial breast and (or) ovarian cancer. Mutations of these two genes could explain 5.5% (2-7%) of ovarian cancers. The hMLH1,...

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