Article
Neuroendocrine phenotype differentiation in a hamster lung epithelial cell line under low oxygen pressure or after transformation by diethylnitrosamine.
Toxicology letters - 1 Jun 1994
Emura M, Ochiai A, Gobert-Bohlen A, Panning B, Dungworth D L
Abstract excerpt
Oxygen pressure as low as 5% in the gas phase or 87 mmHg in the liquid phase induced various neuroendocrine cell (NEC) phenotypes in more than 80% of cells of a cloned fetal Syrian hamster lung epithelial cell line (M3E3/C3). Further, cells from a number of colonies transformed in an anchorage-in...
Topics
- Animals
- Cell Adhesion
- Cell Differentiation
- Cell Hypoxia
- Cell Line
- Cell Transformation, Neoplastic
- Cricetinae
- Culture Media
- Diethylnitrosamine
- Epithelial Cells
- Epithelium
- Female
- Lung
- Mesocricetus
- Neurosecretory Systems
- Oxygen
- Phenotype
- Pressure