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Article

Mapping of herpes simplex virus 1 genes with mutations which overcome host restrictions to infection.

Proceedings of the National Academy of Sciences of the United States of America - 7 Jun 1994

Brandimarti R, Huang T, Roizman B, Campadelli-Fiume G

Abstract excerpt

Earlier studies have shown that the thymidine kinase-negative baby hamster kidney (BHKTK-) cell lines expressing constitutively the herpes simplex virus 1 (HSV-1) glycoprotein D (gD), designated BJ, restrict infection by HSV-1 at the level of virus entry. U10, a HSV-1 mutant not restricted by the BJ cells, carried the substitution of proline for Leu25 in the gD gene, suggesting that gD encodes a specialized...

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Identifiers

PMID: 8202498
DOI: 10.1073/pnas.91.12.5406
PMCID: PMC44004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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