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Article

Mapping of herpes simplex virus 1 genes with mutations which overcome host restrictions to infection.

Proceedings of the National Academy of Sciences of the United States of America - 7 Jun 1994

Brandimarti R, Huang T, Roizman B, Campadelli-Fiume G

Abstract excerpt

Earlier studies have shown that the thymidine kinase-negative baby hamster kidney (BHKTK-) cell lines expressing constitutively the herpes simplex virus 1 (HSV-1) glycoprotein D (gD), designated BJ, restrict infection by HSV-1 at the level of virus entry. U10, a HSV-1 mutant not restricted by the...

Topics

Animals
Cell Line
Cricetinae
Genes, Viral
Herpes Simplex
Herpesvirus 1, Human
Mutation
Viral Envelope Proteins
Viral Structural Proteins
Virus Replication

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8202498
DOI: 10.1073/pnas.91.12.5406
PMCID: PMC44004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8202498-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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