Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic mapping of two new blood pressure quantitative trait loci in the rat by genotyping endothelin system genes.

The Journal of clinical investigation - 1 Jun 1994

Deng A Y, Dene H, Pravenec M, Rapp J P

Abstract excerpt

The endothelin system, consisting of a series of potent vasoconstrictor peptides and their receptors, is potentially important in the control of blood pressure. We found that the gene coding for endothelin-2 (ET2), also known as vasoctive intestine peptide, cosegregated strongly with systolic blood pressure in a F2 population [F2(S x LEW)] derived from a cross of the Dahl salt-sensitive (S) rat and the Lewis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Blood Pressure
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Molecular Sequence Data

Share to Rats, Inbred Strains

Share to Rats, Wistar

Source

Open in PubMed Open full text

Identifiers

PMID: 8201007
DOI: 10.1172/JCI117284
PMCID: PMC294520

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic mapping of two new blood pressure quantitative trait loci in the rat by genotyping endothelin system genes.PMID 8201007Read ↗

Quantitative trait loci in genetically hypertensive rats. Possible sex specificity.Semantic proximity Read ↗

Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat.Semantic proximity Read ↗

Genomic map of cardiovascular phenotypes of hypertension in female Dahl S rats.Semantic proximity Read ↗

Fine mapping of epistatic genetic determinants of blood pressure on rat chromosome 5.Semantic proximity Read ↗

Fine-mapping and comprehensive transcript analysis reveals nonsynonymous variants within a novel 1.17 Mb blood pressure QTL region on rat chromosome 10.Semantic proximity Read ↗

Mapping of rat chromosome 2 markers generated from chromosome-sorted DNA.Semantic proximity Read ↗

Two closely linked interactive blood pressure QTL on rat chromosome 5 defined using congenic Dahl rats.Semantic proximity Read ↗

Genetic mapping of two blood pressure quantitative trait loci on rat chromosome 1.Semantic proximity Read ↗

Defining a rat blood pressure quantitative trait locus to a <81.8 kb congenic segment: comprehensive sequencing and renal transcriptome analysis.Semantic proximity Read ↗

Locating a blood pressure quantitative trait locus within 117 kb on the rat genome: substitution mapping and renal expression analysis.Semantic proximity Read ↗

Complete genome searches for quantitative trait loci controlling blood pressure and related traits in four segregating populations derived from Dahl hypertensive rats.Semantic proximity Read ↗

Fine linkage mapping of the blood pressure quantitative trait locus region on rat chromosome 1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.