Article
Genetic mapping of two new blood pressure quantitative trait loci in the rat by genotyping endothelin system genes.
The Journal of clinical investigation - 1 Jun 1994
Deng A Y, Dene H, Pravenec M, Rapp J P
Abstract excerpt
The endothelin system, consisting of a series of potent vasoconstrictor peptides and their receptors, is potentially important in the control of blood pressure. We found that the gene coding for endothelin-2 (ET2), also known as vasoctive intestine peptide, cosegregated strongly with systolic blo...
Topics
- Animals
- Base Sequence
- Blood Pressure
- Chromosome Mapping
- Endothelins
- Genotype
- Molecular Sequence Data
- Rats
- Rats, Inbred Strains
- Rats, Wistar