Article
Global patterns of human DNA sequence variation in a 10-kb region on chromosome 1.
Molecular biology and evolution - 1 Feb 2001
Yu N, Zhao Z, Fu Y X, Sambuughin N, Ramsay M, Jenkins T, Leskinen E, Patthy L, Jorde L B, Kuromori T, Li W H
Abstract excerpt
Human DNA variation is currently a subject of intense research because of its importance for studying human origins, evolution, and demographic history and for association studies of complex diseases. A approximately 10-kb region on chromosome 1, which contains only four small exons (each <155 bp), was sequenced for 61 humans (20 Africans, 20 Asians, and 21 Europeans) and for 1 chimpanzee, 1 gorilla, and 1...
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