Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allelic polymorphisms and RFLP in the human immunoglobulin lambda light chain locus.

Human genetics - 1 May 1999

Lefranc M P, Pallarès N, Frippiat J P

Abstract excerpt

The organization of the human immunoglobulin lambda light chain locus (IGL) was recently described. This locus has been entirely sequenced. To evaluate the extent of the genomic variability existing inside that locus, we compiled all the available sequences of germline IGLV genes to find variants of Vlambda sequences. We also looked for RFLP polymorphisms in a reputedly highly polymorphic human population from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Restriction Enzymes
Share to DNA Transposable Elements
Share to Ethnicity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Immunoglobulin

Share to Immunoglobulin lambda-Chains

Share to Racial Groups

Share to Restriction Mapping

Share to Sequence Deletion

Source

Identifiers

PMID: 10394926
DOI: 10.1007/s004390050969

Genes

IGL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allelic polymorphisms and RFLP in the human immunoglobulin lambda light chain locus.PMID 10394926Read ↗

Unveiling the Diversity of Immunoglobulin Heavy Constant Gamma (IGHG) Gene Segments in Brazilian Populations Reveals 28 Novel Alleles and Evidence of Gene Conversion and Natural SelectionSemantic proximity Read ↗

Genomic EcoRI polymorphism and cosmid sequencing reveal an insertion/deletion and a new IGLV5 allele in the human immunoglobulin lambda variable locus (22q11.2/IGLV).Semantic proximity Read ↗

Genetic diversity of the human immunoglobulin heavy chain VH region.Semantic proximity Read ↗

Notes on individual sequence variation in humans: immunoglobulin kappa light chain.Semantic proximity Read ↗

Polymorphisms and haplotypes in the human immunoglobulin kappa locus.Semantic proximity Read ↗

Sequence analysis of light chain genes from human intestinal plasma cells demonstrates that lambda genes are almost all in-frame and highly mutated and most kappa genes are highly mutated when in-frame and minimally mutated when out-of-frame.Semantic proximity Read ↗

RFLP of human immunoglobulin genes.Semantic proximity Read ↗

Extensive allelic sequence variation in the J region of the human immunoglobulin heavy chain gene locus.Semantic proximity Read ↗

Polymorphism of the human Ig VH4 gene family.Semantic proximity Read ↗

HindIII restriction fragment alleles of the human immunoglobulin V lambda II subgroup genes.Semantic proximity Read ↗

MspI RFLP of the human TCR gamma chain variable gene V9 (TCRGV9).Semantic proximity Read ↗

Genetic diversity at the hinge region of the unique immunoglobulin heavy gamma (IGHG) gene in leporids (Oryctolagus, Sylvilagus and Lepus).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.