Article
One-megabase sequence analysis of the human immunoglobulin lambda gene locus.
Genome research - 1 Mar 1997
Kawasaki K, Minoshima S, Nakato E, Shibuya K, Shintani A, Schmeits J L, Wang J, Shimizu N
Abstract excerpt
A total of 1,025,415 bases of nucleotide sequence, including the entire human immunoglobulin lambda gene locus has been determined. This is the largest contiguous human DNA sequence ever published. The sequence data revealed the organization of 36 potentially active V lambda gene segments, 33 pse...
Topics
- Alleles
- Alternative Splicing
- Amino Acid Sequence
- Base Sequence
- Chromosome Mapping
- Cloning, Molecular
- Cosmids
- DNA
- DNA Mutational Analysis
- Exons
- Gene Expression
- Humans
- Immunoglobulin Constant Regions
- Immunoglobulin Joining Region
- Immunoglobulin Variable Region
- Immunoglobulin lambda-Chains
- Introns
- Molecular Sequence Data