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Article

Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori.

Antimicrobial agents and chemotherapy - 1 Feb 1996

Versalovic J, Shortridge D, Kibler K, Griffy M V, Beyer J, Flamm R K, Tanaka S K, Graham D Y, Go M F

Abstract excerpt

Twelve clarithromycin-resistant Helicobacter pylori isolates (100% of resistant isolates examined) from seven different patients each contained an A-->G transition mutation within a conserved loop of 23S rRNA. A-->G transition mutations at positions cognate with Escherichia coli 23S rRNA positions 2058 and 2059 were identified. Clarithromycin-susceptible H. pylori isolates from 14 different patients displayed no...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 8834903
DOI: 10.1128/AAC.40.2.477
PMCID: PMC163139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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