Article
Pax-2 is required for mesenchyme-to-epithelium conversion during kidney development.
Development (Cambridge, England) - 1 Nov 1993
Rothenpieler U W, Dressler G R
Abstract excerpt
The conversion of mesenchyme to epithelium during the embryonic development of the mammalian kidney requires reciprocal inductive interactions between the ureter and the responding metanephric mesenchyme. The Pax-2 gene is activated in the mesenchyme in response to induction and is subsequently d...
Topics
- Animals
- Base Sequence
- DNA, Antisense
- DNA-Binding Proteins
- Epithelium
- Immunohistochemistry
- Kidney
- Mesoderm
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data
- Morphogenesis
- Organ Culture Techniques
- PAX2 Transcription Factor
- Phenotype
- Transcription Factors