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Article

The metanephric blastema differentiates into collecting system and nephron epithelia in vitro

1 Oct 1995

Abstract excerpt

The kidney forms from two tissue populations derived from intermediate mesoderm, the ureteric bud and metanephric mesenchyme. It is currently accepted that metanephric mesenchyme is committed to differentiating into nephrons while the ureteric bud is restricted to forming the renal collecting system. To test this hypothesis, we transferred lacZ into pure metanephric mesenchyme isolated from gestation day 13 rat...

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PMID: 7588055
DOI: 10.1242/dev.121.10.3207

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