Article
Microarray analysis of novel cell lines representing two stages of metanephric mesenchyme differentiation.
Mechanisms of development - 1 Mar 2002
Valerius M Todd, Patterson Larry T, Witte David P, Potter S Steven
Abstract excerpt
Clonal cell lines representing different developmental stages of the metanephric mesenchyme were made from transgenic mice with the Simian Virus 40 T-antigen (SV40 Tag) gene driven by the Hoxa 11 promoter. The resulting mK3 cell line represented early metanephric mesenchyme, prior to induction by the ureteric bud. These cells showed a spindle-shaped, fibroblast morphology. They expressed genes characteristic of...
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