Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of Pax-2 regulatory sequences that direct transgene expression in the Wolffian duct and its derivatives.

Developmental biology - 1 Jan 2001

Kuschert S, Rowitch D H, Haenig B, McMahon A P, Kispert A

Abstract excerpt

The Pax family of transcription factors plays important roles in vertebrate organogenesis. Pax-2 is a critical factor in the development of the mammalian urogenital system. Pax-2 is expressed in the epithelia of the ureter, the Müllerian duct, and the Wolffian duct and in the nephrogenic mesenchyme. Gene targeting in the mouse as well as natural mutations in mouse and man have demonstrated the requirement of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epithelium
Share to Genes, Reporter
Share to In Situ Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Mutant Strains

Share to PAX2 Transcription Factor

Share to Regulatory Sequences, Nucleic Acid

Share to Transgenes

Share to Ureter

Source

Identifiers

PMID: 11133159
DOI: 10.1006/dbio.2000.9971

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of Pax-2 regulatory sequences that direct transgene expression in the Wolffian duct and its derivatives.PMID 11133159Read ↗

<i>Pax-2</i> controls multiple steps of urogenital developmentSemantic proximity Read ↗

Two novel EGFP insertion alleles reveal unique aspects of Pax2 function in embryonic and adult kidneys.Semantic proximity Read ↗

The role of PAX2 in normal and abnormal development of the urinary tract.Semantic proximity Read ↗

Pax2/8-regulated Gata3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidneySemantic proximity Read ↗

PAX2 Activates WNT4 Expression during Mammalian Kidney DevelopmentSemantic proximity Read ↗

Understanding normal and abnormal development of the Wolffian/epididymal duct by using transgenic miceSemantic proximity Read ↗

Deletion of Fibroblast Growth Factor Receptor 2 from the Peri-Wolffian Duct Stroma Leads to Ureteric Induction Abnormalities and Vesicoureteral RefluxSemantic proximity Read ↗

Characterization of the murine Lbx2 promoter, identification of the human homologue, and evaluation as a candidate for Alström syndrome.Semantic proximity Read ↗

Multiple, distant Gata2 enhancers specify temporally and tissue-specific patterning in the developing urogenital system.Semantic proximity Read ↗

Pax-2 is required for mesenchyme-to-epithelium conversion during kidney development.Semantic proximity Read ↗

Ret-Dependent Cell Rearrangements in the Wolffian Duct Epithelium Initiate Ureteric Bud MorphogenesisSemantic proximity Read ↗

Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.