Article
Autoimmunity to ryanodine receptor and titin in myasthenia gravis is associated with GM allotypes.
Autoimmunity - 1 Jan 1997
Skeie G O, Pandey J P, Aarli J A, Gilhus N E
Abstract excerpt
Myasthenia gravis (MG) is mediated by autoantibodies against the acetylcholine receptor at the muscle endplate. Some MG patients have in addition antibodies (Ab) to the skeletal muscle proteins ryanodine receptor (RyR) and titin. We have examined GM and KM allotypes, RyR and titin Ab in 44 MG patients (37 thymoma patients and 7 non-thymoma, late-onset patients) and 292 non-MG controls to see if GM/KM allotypes...
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