Autoimmunity to ryanodine receptor and titin in myasthenia gravis is associated with GM allotypes.

doi:10.3109/08916939709003854

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Article

Autoimmunity to ryanodine receptor and titin in myasthenia gravis is associated with GM allotypes.

Autoimmunity - 1 Jan 1997

Skeie G O, Pandey J P, Aarli J A, Gilhus N E

Abstract excerpt

Myasthenia gravis (MG) is mediated by autoantibodies against the acetylcholine receptor at the muscle endplate. Some MG patients have in addition antibodies (Ab) to the skeletal muscle proteins ryanodine receptor (RyR) and titin. We have examined GM and KM allotypes, RyR and titin Ab in 44 MG pat...

Topics

Adult
Aged
Autoantibodies
Blotting, Western
Calmodulin-Binding Proteins
Carrier Proteins
Connectin
Enzyme-Linked Immunosorbent Assay
Female
Germany
Haplotypes
Hemagglutination Tests
Humans
Immunoglobulin Gm Allotypes
Male
Membrane Proteins
Middle Aged
Muscle Proteins

Source

Open in PubMed

Identifiers

PMID: 9546812
DOI: 10.3109/08916939709003854

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9546812-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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