Article
p53 mutations in gastric and colorectal cancers in Texas Hispanics versus Anglos.
Virchows Archiv : an international journal of pathology - 1 Jan 1994
Schneider B G, Hilsenbeck S G, Hensel C H, Pekkel V, Shelton C H, Rodríguez-Martínez H A, Gutiérrez-Díaz M E, Pulitzer D R, Allred D C
Abstract excerpt
Gastric cancer is more than twice as common in Hispanics as in Anglos in Texas, while colorectal cancer is almost twice as common in Anglos as Hispanics. To test the hypothesis that mutations in the p53 tumour suppressor gene are involved in these differences, we examined 131 gastric and 138 colorectal cancers from Hispanic and Anglo patients from South Texas and Mexico using immunohistochemistry (IHC) as a...
Topics
- Base Sequence
- Codon
- Colorectal Neoplasms
- Exons
- Female
- Genes, p53
- Hispanic or Latino
- Humans
- Immunohistochemistry
- Male
- Mexico