Article
Rates of TP53 Mutation are Significantly Elevated in African American Patients with Gastric Cancer.
Annals of surgical oncology - 1 Jul 2018
van Beek Elke J A H, Hernandez Jonathan M, Goldman Debra A, Davis Jeremy L, McLaughlin Kaitlin, Ripley R Taylor, Kim Teresa S, Tang Laura H, Hechtman Jaclyn F, Zheng Jian, Capanu Marinela, Schultz Nikolaus, Hyman David M, Ladanyi Marc, Berger Michael F, Solit David B, Janjigian Yelena Y, Strong Vivian E
Abstract excerpt
BACKGROUND: Gastric adenocarcinoma is a heterogenous disease that results from complex interactions between environmental and genetic factors, which may contribute to the disparate outcomes observed between different patient populations. This study aimed to determine whether genomic differences exist in a diverse population of patients by evaluating tumor mutational profiles stratified by race. METHODS: All...
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