Article
The stem-loop structure of the cis-encapsidation signal is highly conserved in naturally occurring hepatitis B virus variants.
Virology - 1 May 1994
Laskus T, Rakela J, Persing D H
Abstract excerpt
The region encoding the stem-loop structure of the HBV cis-encapsidation signal was sequenced in 87 patients with various forms of hepatitis. Altogether, 20 nucleotide substitutions were found; 15/20 were predicted to increase the stability of the stem-loop structure. Substitutions likely to decrease the stability of the cis-encapsidation signal were not observed.
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