The stem-loop structure of the cis-encapsidation signal is highly conserved in naturally occurring hepatitis B virus variants.

doi:10.1006/viro.1994.1247

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Article

The stem-loop structure of the cis-encapsidation signal is highly conserved in naturally occurring hepatitis B virus variants.

Virology - 1 May 1994

Laskus T, Rakela J, Persing D H

Abstract excerpt

The region encoding the stem-loop structure of the HBV cis-encapsidation signal was sequenced in 87 patients with various forms of hepatitis. Altogether, 20 nucleotide substitutions were found; 15/20 were predicted to increase the stability of the stem-loop structure. Substitutions likely to decr...

Topics

Base Sequence
Capsid
Conserved Sequence
Genetic Variation
Hepatitis B
Hepatitis B virus
Humans
Molecular Sequence Data
Nucleic Acid Conformation
Regulatory Sequences, Nucleic Acid
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid

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