Article
Prognostic value and clinicopathologic correlation of p53 gene mutations and nuclear DNA content in human lung cancer: a prospective study.
Journal of surgical oncology - 1 May 1994
Casson A G, McCuaig S, Craig I, Ayed A, Inculet R, Kerkvliet N, O'Malley F
Abstract excerpt
The aim of this prospective study was to determine whether use of a combination of biomarkers, p53 and nuclear DNA content, led to improved prognosis and clinicopathologic correlation in human non-small cell lung cancer. Nineteen patients undergoing curative resection of primary non-small cell lu...
Topics
- Adult
- Aged
- Base Sequence
- Carcinoma
- DNA, Neoplasm
- Female
- Flow Cytometry
- Genes, p53
- Humans
- Immunoenzyme Techniques
- Lung Neoplasms
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Ploidies
- Polymerase Chain Reaction
- Polymorphism, Genetic