Article
Serum antibody response to B. pertussis Tn5 mutants, purified PT and FHA in two different mouse strains and passive protection in the murine intranasal infection model.
Microbial pathogenesis - 1 Jan 1990
Olander R M, Muotiala A, Karvonen M, Kuronen T, Runeberg-Nyman K
Abstract excerpt
The protective capacities of antibodies to pertussis toxin (PT) were compared with antibodies to several other pertussis antigens in an experimental murine model of intranasal infection with Bordetella pertussis. Protection from lethal challenge was achieved by passive immunization with mouse ant...
Topics
- Animals
- Antibodies, Bacterial
- Bordetella Infections
- Bordetella pertussis
- DNA Transposable Elements
- Female
- Hemagglutinins
- Immunization, Passive
- Mice
- Mutation
- Neutralization Tests
- Pertussis Toxin
- Pertussis Vaccine
- Virulence Factors, Bordetella