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Article

Brain-specific enhancement of the mouse neurofilament heavy gene promoter in vitro.

The Journal of biological chemistry - 6 May 1994

Schwartz M L, Katagi C, Bruce J, Schlaepfer W W

Abstract excerpt

We have investigated the DNA elements responsible for transcription from the proximal portion of the mouse neurofilament heavy gene (NF-H) promoter by in vitro transcription using extracts from expressing (brain) and non-expressing (liver) tissues. We have found that constructs containing 5' region from -1314 to -115 exhibit a 3-5-fold higher level of NF-H promoter activity, relative to the adenovirus major late...

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PMID: 8175776

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