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Article

Opposing roles of Elk-1 and its brain-specific isoform, short Elk-1, in nerve growth factor-induced PC12 differentiation.

The Journal of biological chemistry - 16 Feb 2001

Vanhoutte P, Nissen J L, Brugg B, Gaspera B D, Besson M J, Hipskind R A, Caboche J

Abstract excerpt

The ternary complex factor Elk-1, a major nuclear target of extracellular signal-regulated kinases, is a strong transactivator of serum-responsive element (SRE) driven gene expression. We report here that mature brain neurons and nerve growth factor (NGF)-differentiated PC12 cells also express a...

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Source

Identifiers

PMID: 11050086
DOI: 10.1074/jbc.M006678200

Genes

NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11050086-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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