Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dystrophin is transcribed in brain from a distant upstream promoter.

15 Feb 1991

Abstract excerpt

Dystrophin, the protein product of the Duchenne muscular dystrophy gene, is expressed in brain as well as muscle. The role of dystrophin in the brain is not clear, though one-third of Duchenne muscular dystrophy patients exhibit some degree of mental retardation. We have isolated the genomic region encoding the alternative 5' terminus of dystrophin used in the brain. Primer extension and polymerase chain reaction...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Muscle Physiology and Disorders
Share to Silk-based biomaterials and applications
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1996328
DOI: 10.1073/pnas.88.4.1276

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dystrophin is transcribed in brain from a distant upstream promoter.PMID 1996328Read ↗

Neuronal SH-SY5Y cells use the C-dystrophin promoter coupled with exon 78 skipping and display multiple patterns of alternative splicing including two intronic insertion events.Semantic proximity Read ↗

Identification of a novel first exon in the human dystrophin gene and of a new promoter located more than 500 kb upstream of the nearest known promoter.Semantic proximity Read ↗

Structural diversity despite strong evolutionary conservation in the 5'-untranslated region of the P-type dystrophin transcript.Semantic proximity Read ↗

Distal transcript of the dystrophin gene initiated from an alternative first exon and encoding a 75-kDa protein widely distributed in nonmuscle tissues.Semantic proximity Read ↗

β-dystrobrevin, a member of the dystrophin-related protein familySemantic proximity Read ↗

A novel product of the Duchenne muscular dystrophy gene which greatly differs from the known isoforms in its structure and tissue distribution.Semantic proximity Read ↗

PCR analysis of dystrophin gene mutation and expression.Semantic proximity Read ↗

Cloning and characterization of promoter and 5'-UTR of the NMDA receptor subunit epsilon 2: evidence for alternative splicing of 5'-non-coding exon.Semantic proximity Read ↗

Gene structure of mammalian acetylcholinesterase. Alternative exons dictate tissue-specific expression.Semantic proximity Read ↗

Expression of three alternative acetylcholinesterase messenger RNAs in human tumor cell lines of different tissue origins.Semantic proximity Read ↗

Identification of a mutation in the promoter region of the dystrophin gene in a patient with atypical Becker muscular dystrophy.Semantic proximity Read ↗

Loss of Dp140 dystrophin isoform and intellectual impairment in Duchenne dystrophySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.