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Article

Transcription factors induced by interferons alpha and gamma.

Nucleic acids research - 25 Nov 1990

Imam A M, Ackrill A M, Dale T C, Kerr I M, Stark G R

Abstract excerpt

Factors induced by interferons (IFNs) bind to the IFN-stimulated response elements (ISREs) of many genes. In human cells treated with type I (alpha, beta) IFN, factor E is induced in about 1 min and factor M after about 1 hr. Factor G is induced after about 1 hr in cells treated with type II (gamma) IFN. G and M have very similar positions in bandshift assays, sensitivities to cycloheximide, footprints on an ISRE...

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Identifiers

PMID: 2123539
DOI: 10.1093/nar/18.22.6573
PMCID: PMC332612

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