Article
Differential neurophysin immunoreactivities in solitary magnocellular neurons of the homozygous Brattleboro rat indicate an altered neurophysin moiety.
Brain research - 28 Jan 1994
van Leeuwen F W, Evans D A, Meloen R, Sonnemans M A
Abstract excerpt
In the homozygous Brattleboro rat (di/di) a single base deletion in the vasopressin (VP) gene causes diabetes insipidus, resulting in the synthesis of a VP precursor with a different C-terminus. We reported previously that a small number of post-mitotic VP neurons in di/di rats undergo a switch t...
Topics
- Aging
- Amino Acid Sequence
- Animals
- Female
- Homozygote
- Immunohistochemistry
- Linear Models
- Male
- Molecular Sequence Data
- Neurons
- Neurophysins
- Phenotype
- Rats
- Rats, Brattleboro
- Solitary Nucleus
- Vasopressins