Article
HLA-DR alleles in patients with Sjögren's syndrome over-representing V beta 2 and V beta 13 genes in the labial salivary glands.
British journal of rheumatology - 1 May 1994
Sumida T, Sakamaki T, Yonaha F, Maeda T, Namekawa T, Nawata Y, Takabayashi K, Iwamoto I, Yoshida S
Abstract excerpt
To identify genetic factors that play a role in the pathogenesis of patients with SS over-representing V beta 2 and V beta 13 genes in the lips, HLA-DR and -DQ alleles of 10 primary SS patients with predominant expression of V beta 2 and V beta 13 genes in the lips were analysed, using the polymerase chain reaction (PCR) and sequence specific oligonucleotide probes. The CDR3 amino acid sequences of cDNA clones...
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